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Advanced Histological Techniques


Immunohistochemistry is the application of antibody/antigen interactions to provide information about biological systems.

Antibody Binding

The antibody systems used in Immunohistochemistry can be broadly divided into two types, direct and indirect.

Detection Systems in Immunohistochemistry

Light microscopy makes use of primarily two detection systems for immunohistochemistry - fluorescence and enzyme labeling, while electron microsco

Electron Microscopy

The resolution of a microscope is limited by the wavelength of light passing through the sample.

Fixing Tissue for Electron Microscopy

The most popular fixatives for TEM work are aldehydes and osmium tetroxide.


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