Applications of Denaturing DNA and RNA Gels

RNA Mapping

In studies of transcriptional regulation, it is often necessary to determine the structure and/or amount of a given RNA species.

S1 Mapping

Nuclease S1 will digest only ssDNA or ssRNA.

Primer Extension

Primer extension is another technique used to analyze RNA structure and expression.

Analysis of DNA/Protein Interactions

The binding of proteins to specific DNA sites is an important mechanism of cellular regulation.

Methylation & Uracil Interference Assays

Both the methylation and uracil interference assay analytical methods are presented in parallel because they assay for similar information based o


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