Version 3.2
Date revised: 8/8/2023
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]
H302 - Acute Toxicity-Oral (Category 4)
H305 - Aspiration Hazard (Category 2)
H312 - Acute Toxicity-Dermal (Category 4)
H319 - Serious Eye Damage/Eye Irritation (Category 2A)
H332 - Acute Toxicity-Inhalation (Category 4)
H411 - Chronic Hazards to the Aquatic Environment (Category 2)
2.2 Label Elements
| GHS Label Elements | ||
 |  | DANGER H302 - Harmful if swallowed |
 | ||
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Blend of nonionic surfactants and scintillators in chiral phenylalkanes.
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Phenyl Xylyl Ethane (PXE) | 55 - 70 | 6196-95-8 | 228-249-2 | H304, H315, H319 |
| Linear alkyl phenyl ethoxylates | 30 - 40 | 9016-45-9 | 500-024-6 | H315, H319, H411 |
| Methanol | 1 - 3 | 67-56-1 | 200-659-6 | H225, H301, H311, H331 |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Do not induce vomiting, because of danger of aspiration into the lungs. Get medical attention immediately. Adverse effects of aspiration into the lungs may be delayed up to 48 hours.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Phenyl Xylyl Ethane (PXE):
Sore throat, coughing, labored breathing, sneezing and burning sensation, depending on the concentration and duration of exposure. May cause central nervous system depression or effects. Symptoms may include headache, excitation, euphoria, dizziness, incoordination, drowsiness, light-headedness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death, depending on the concentration and duration of exposure.
Linear alkyl phenyl ethoxylates:
Discomfort in nose and throat, nasal discharge, coughing, difficulty breathing.
Methanol:
Irritation of the respiratory tract and mucous membranes. For central nervous system symptoms which may occur due to exposure by inhalation, see Ingestion.
Ingestion
Phenyl Xylyl Ethane (PXE):
Salivation, pain, nausea, vomiting and diarrhea. Exposure may also cause central nervous system symptoms similar to those listed under Inhalation.
Linear alkyl phenyl ethoxylates:
Abdominal discomfort, nausea, and diarrhea.
Methanol:
Effects may include excitation, euphoria, headache, dizziness, drowsiness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death.
Skin
Phenyl Xylyl Ethane (PXE):
Drying, reddening, itching, and cracking. Repeated or prolonged contact with large amounts of this material may result in absorption through the skin to produce toxic effects.
Linear alkyl phenyl ethoxylates:
Local redness and swelling.
Methanol:
Exposure may cause symptoms similar to those listed under Ingestion.
Eyes
Phenyl Xylyl Ethane (PXE):
Redness, tearing, and blurred vision.
Linear alkyl phenyl ethoxylates:
Excess blinking and tear production. Marked redness and swelling of the eye with injury to the cornea.
Methanol:
Irritation, redness, pain, and inflammation.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Water spray, dry chemical, alcohol-resistant foam, or carbon dioxide.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Fires involving this product may release carbon monoxide, carbon dioxide, reactive hydrocarbons and irritating vapors.
Hazardous Decomposition Products
Combustion may produce toxic oxides of carbon, nitrogen, sulfur and reactive hydrocarbons.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Eliminate source of ignition. Ventilate area. Cover with absorbent material (dry sand or earth) to confine spill and sweep or shovel into container. Close container tightly. Avoid breathing vapors.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Do not eat, drink, or smoke in areas of use or storage.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage.
Incompatibles
Phenyl Xylyl Ethane (PXE):
Oxidizing agents.
Linear alkyl phenyl ethoxylates:
Oxidizing agents.
Methanol:
Incompatible with acetyl bromide, calcium carbide, chlorine, chromic anhydride, cyanuric chloride, dichloromethane, diethyl zinc, lead perchlorate, magnesium, metals, strong oxidizers, perchloric acid, phosphorous trioxide, potassium, sodium hypochlorite, sulfuric acid, and zinc.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Phenyl Xylyl Ethane (PXE)
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
Component: Linear alkyl phenyl ethoxylates
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
Component: Methanol
ACGIH Threshold Limit Value (TLV):
200 ppm
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear protective gloves and clean body covering clothing.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, blue-violet fluorescent liquid | b. Odor | Odorless |
| c. Odor Threshold | N.A. | d. pH | N.A. |
| e. Melting/Freezing Point (oC) | 0 | f. Boiling point (oC) | 302-318 |
| g. Flash Point (oC) | 74 | h. Evaporation Rate | Not measureable |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.D. |
| k. Vapor Pressure | < 0.1 | l. Vapor Density (Air = 1) | Not determinable |
| m. Relative Density | 0.91 | n. Water Solubility | 30% by weight @ 20C |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.D. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | 32.0 cSt @ 20 C |
| s. Explosive Properties | Can be made to burn | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Material can be made to burn; combustion is generally not self-sustaining. Reacts with oxidizers
10.2 Chemical Stability
Stable under ordinary conditions of use and storage.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Heat, sources of ignition.
10.5 Incompatible Materials
Phenyl Xylyl Ethane (PXE):
Oxidizing agents.
Linear alkyl phenyl ethoxylates:
Oxidizing agents.
Methanol:
Incompatible with acetyl bromide, calcium carbide, chlorine, chromic anhydride, cyanuric chloride, dichloromethane, diethyl zinc, lead perchlorate, magnesium, metals, strong oxidizers, perchloric acid, phosphorous trioxide, potassium, sodium hypochlorite, sulfuric acid, and zinc.
10.6 Hazardous Decomposition Products
Combustion may produce toxic oxides of carbon, nitrogen, sulfur and reactive hydrocarbons.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
No data.
Dermal Rabbit LD50 (mg/kg)
No data.
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Phenyl Xylyl Ethane (PXE) | No | No | None |
| Linear alkyl phenyl ethoxylates | No | No | None |
| Methanol | No | No | None |
Potential Health Effects
Inhalation
Phenyl Xylyl Ethane (PXE)
Breathing of the mists, vapors or fumes may irritate the nose, throat and lungs.
Linear alkyl phenyl ethoxylates
Vapors or mist, expecially as generated from heating the material or as from exposure in poorly ventilated areas or confined spaces, may be irritating and cause discomfort in nose and throat. Prolonged exposure may cause difficulty breathing.
Methanol
May irritate the respiratory tract and mucuous membranes. Exposure may cause central nervous system symptoms similar to those listed under Ingestion.
Ingestion
Phenyl Xylyl Ethane (PXE)
May cause irritation of the mouth, throat, and gastrointestinal tract. Exposure may also cause central nervous system symptoms.
Linear alkyl phenyl ethoxylates
May be harmful by ingestion.
Methanol
Primary toxic effects are metabolic acidosis and visual system damage. Visual system damage may progress from visual blurring to complete blindness. May cause harmful central nervous system effects which may be delayed.
Skin
Phenyl Xylyl Ethane (PXE)
May cause skin irritation.
Linear alkyl phenyl ethoxylates
Brief contact may cause slight irritation. Prolonged contact, as with clothing wetted with material, may cause more severe irritation and discomfort.
Methanol
Absorption from prolonged or massive skin contact may cause poisoning. Repeated or prolonged contact may result in defatting, redness, itching, inflammation, cracking and possible secondary infection. Exposure may cause symptoms similar to those listed under Ingestion.
Eyes
Phenyl Xylyl Ethane (PXE)
Exposure to vapors, fumes or mists may cause irritation. Direct contact may cause irritation.
Linear alkyl phenyl ethoxylates
Causes irritation and possible injury to the cornea.
Methanol
Exposure to liquid, vapors, fumes or mists may cause irritation. Direct contact may cause irritation, pain, corneal inflammation and possible corneal damage.
Carcinogenicity
Phenyl Xylyl Ethane (PXE)
Not listed by NTP or IARC as a known or possible carcinogen.
Linear alkyl phenyl ethoxylates
Not listed by NTP or IARC as a known or possible carcinogen.
Methanol
This component is not listed as a carcinogen by NTP or IARC.
Mutagenicity
Phenyl Xylyl Ethane (PXE)
No information available.
Linear alkyl phenyl ethoxylates
No information available.
Methanol
No information available.
Reproductive Toxicity
Phenyl Xylyl Ethane (PXE)
No information available.
Linear alkyl phenyl ethoxylates
No information available.
Methanol
Possible reproductive hazard.
Teratogenic Effects
Phenyl Xylyl Ethane (PXE)
No information available.
Linear alkyl phenyl ethoxylates
No information available.
Methanol
No information available.
Routes of Entry
Phenyl Xylyl Ethane (PXE)
Ingestion, inhalation, skin contact.
Linear alkyl phenyl ethoxylates
Ingestion, inhalation.
Methanol
Inhalation, ingestion, or skin contact.
Target Organ Statement
Phenyl Xylyl Ethane (PXE)
No information available.
Linear alkyl phenyl ethoxylates
No information available.
Methanol
Chronic intoxication may cause degenerative changes in liver, kidneys, brain, gastrointestinal tract, and heart muscle. Persons with pre-existing liver impairment, skin and respiratory disorders may be at an increased risk from exposure.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Phenyl Xylyl Ethane (PXE)
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Linear alkyl phenyl ethoxylates
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | LC50(48hrs, daphnia) 1.821 mg/L | EC50 (48hrs) 20 mg/L | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Methanol
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Phenyl Xylyl Ethane (PXE)
No data
Linear alkyl phenyl ethoxylates
Readily biodegradable >97% elimination in 30 days
Methanol
No data
12.3 Bioaccumulative Potential
Phenyl Xylyl Ethane (PXE)
No data
Linear alkyl phenyl ethoxylates
No data
Methanol
No data
12.4 Mobility in Soil
Phenyl Xylyl Ethane (PXE)
No data
Linear alkyl phenyl ethoxylates
No data
Methanol
No data
12.5 Results of PBT and vPvB Assessment
Phenyl Xylyl Ethane (PXE)
No data
Linear alkyl phenyl ethoxylates
Substance is PBT / vPvB
Methanol
No data
12.6 Other Adverse Effects
Phenyl Xylyl Ethane (PXE)
None
Linear alkyl phenyl ethoxylates
None
Methanol
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | UN3082 | N.A. | UN3082 | N.A. |
| 14.2 Shipping Name | Environmentally Hazardous Substance, Liquid, N.O.S. (nonylphenyl ethoxylate) | Not regulated. | Environmentally Hazardous Substance, Liquid, N.O.S. (nonylphenyl ethoxylate) | Not regulated. |
| 14.3 Hazard Class | 9 | N.A. | 9 | N.A. |
| 14.4 Packing Group | III | N.A. | III | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Marine pollutant in excess of 5 kilograms/5 liters | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Phenyl Xylyl Ethane (PXE) | No | No | No | Yes | No |
| Linear alkyl phenyl ethoxylates | No | No | No | Yes | No |
| Methanol | Yes | No | No | Yes | Yes |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
8/8/2023 - Updated Section 14.5
4/26/2019 - Updated Section 1.4
8/14/2015 - Updated Sections 14.1, 14.2, 14.3 and 14.4
5/29/2015 - Updated Sections 2.1 and 3.2
10/8/2013 - Released Version 1.0
NFPA Codes
Health 1 Flammability 2 Reactivity 0
Dangers
Phenyl Xylyl Ethane (PXE)
H304 - May be fatal if swallowed and enters airways.
H315 - Causes skin irritation.
H319 - Causes serious eye irritation.
Linear alkyl phenyl ethoxylates
H315 - Causes skin irritation.
H319 - Causes serious eye irritation.
H411 - Toxic to aquatic life with long lasting effects.
Methanol
H225 - Highly flammable liquid and vapor.
H301 - Toxic if swallowed
H311 - Toxic in contact with skin.
H331 - Toxic if inhaled.
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.