Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Not a hazardous substance or mixture according to regulation (EC) No. 1272/2008.
2.2 Label Elements
This product has no labeling elements associated with EC directives or respective national laws.
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Buffered alternative to tapwater for hematoxylin and Eosin slide bluing.
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Magnesium sulfate | 2 | 10034-99-8 | 231-298-2 | N.A. |
| Nonhazardous Component | 0.2 | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
If irritation develops, remove victim to fresh air. Get medical attention if symptoms persist.
Ingestion
If small quantities are swallowed, rinse out mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious or drowsy person. If large amounts are swallowed or if irritation or discomfort occurs, get medical attention.
Skin
Wash skin with soap and water after handling.
Eyes
Flush eyes with water, holding the eyelids apart. Get medical attention if irritation persists.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Magnesium sulfate:
Symptoms may include coughing and shortness of breath.
Nonhazardous Component:
No information available.
Ingestion
Magnesium sulfate:
Symptoms may include irritation and reddening to the mucous membranes of the mouth, esophagus, and gastrointestinal tract.
Nonhazardous Component:
No information available.
Skin
Magnesium sulfate:
Symptoms may include irritation with redness and pain.
Nonhazardous Component:
No information available.
Eyes
Magnesium sulfate:
Symptoms may include irritation, redness, pain, and corneal damage.
Nonhazardous Component:
No information available.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Use any media that is suitable for the surrounding fire.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Oxides of carbon, sulfur, and magnesium.
Hazardous Decomposition Products
Thermal breakdown of this product during fire or very high heat conditions may evolve the following decomposition products: oxides of carbon, sulfur, and magnesium.
Hazardous Polymerization
N.A.
5.3 Advice for Firefighters
None normally required.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Stop spill at the source if it is safe to do so. Absorb with an inert material and place into an appropriate container for disposal.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact with eyes, skin and clothing. Avoid breathing vapors or mists. Wash thoroughly after handling. Keep containers closed when not in use.
7.2 Conditions for Safe Storage (including any incompatibles)
Store in dark, cool area away from direct sunlight.
Incompatibles
Magnesium sulfate:
No information available
Nonhazardous Component:
Reacts with acids to form carbon dioxide. Dangerous reaction with monoammonium phosphate or a sodium-potassium alloy.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Magnesium sulfate
ACGIH Threshold Limit Value (TLV):
Not listed
OSHA Permissable Exposure Limit (PEL):
Not listed
Component: Nonhazardous Component
ACGIH Threshold Limit Value (TLV):
None established
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
Use with adequate ventilation to minimize exposure.
Respiratory Protection
None.
Eye Protection
Wear safety goggles to prevent splashing.
Skin Protection
None.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, colorless solution | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | 8 |
| e. Melting/Freezing Point (oC) | -5 | f. Boiling point (oC) | 106 |
| g. Flash Point (oC) | N.A. | h. Evaporation Rate | Water |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.A. |
| k. Vapor Pressure | 17 | l. Vapor Density (Air = 1) | 0.62 |
| m. Relative Density | 1.02 | n. Water Solubility | Miscible |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | N.A. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Not reactive under recommended conditions of use.
10.2 Chemical Stability
Stable under normal conditions of use and storage.
10.3 Possibility of Hazardous Reactions
N.A.
10.4 Conditions to Avoid
Strong oxidizing agents.
10.5 Incompatible Materials
Magnesium sulfate:
No information available
Nonhazardous Component:
Reacts with acids to form carbon dioxide. Dangerous reaction with monoammonium phosphate or a sodium-potassium alloy.
10.6 Hazardous Decomposition Products
Thermal breakdown of this product during fire or very high heat conditions may evolve the following decomposition products: oxides of carbon, sulfur, and magnesium.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
N.A.
Dermal Rabbit LD50 (mg/kg)
N.A.
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Magnesium sulfate | No | No | None |
| Nonhazardous Component | No | No | None |
Potential Health Effects
Inhalation
Magnesium sulfate
May be harmful if inhaled. May cause respiratory tract irritation.
Nonhazardous Component
No information available.
Ingestion
Magnesium sulfate
May be harmful if swallowed.
Nonhazardous Component
No information available.
Skin
Magnesium sulfate
May be harmful if absorbed through skin. May cause skin irritation.
Nonhazardous Component
No information available.
Eyes
Magnesium sulfate
May cause eye irritation.
Nonhazardous Component
No information available.
Carcinogenicity
Magnesium sulfate
Not listed by OSHA, ACGIH, NIOSH, NTP or IARC as a known or anticipated carcinogen.
Nonhazardous Component
No information available.
Mutagenicity
Magnesium sulfate
No information available.
Nonhazardous Component
No information available.
Reproductive Toxicity
Magnesium sulfate
No information available.
Nonhazardous Component
No information available.
Teratogenic Effects
Magnesium sulfate
No information available.
Nonhazardous Component
No information available.
Routes of Entry
Magnesium sulfate
Inhalation, ingestion or skin contact.
Nonhazardous Component
No information available.
Target Organ Statement
Magnesium sulfate
No information available
Nonhazardous Component
No information available.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Magnesium sulfate
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | LC50 (48hr, daphnia) 720 | EC50 (18 days) 2700mg/l | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Nonhazardous Component
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr, bluegill) 7100mg/l | LC50 (48hr daphnia) 4100mg/l | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Magnesium sulfate
No data
Nonhazardous Component
No data
12.3 Bioaccumulative Potential
Magnesium sulfate
No data
Nonhazardous Component
No data
12.4 Mobility in Soil
Magnesium sulfate
No data
Nonhazardous Component
No data
12.5 Results of PBT and vPvB Assessment
Magnesium sulfate
not PBT / vPvB
Nonhazardous Component
Not PBT/vPvB
12.6 Other Adverse Effects
Magnesium sulfate
None
Nonhazardous Component
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | N.A. | N.A. | N.A. | N.A. |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All of the components are listed on the TSCA inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Magnesium sulfate | No | No | No | Yes | No |
| Nonhazardous Component | No | No | No | No | No |
Europe
EEC Regulatory
All of the components of this product are listed on the European Inventory of New and Existing Chemical Substances (EINECS) inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
1/9/2014 - Released Version 1.0
NFPA Codes
Health 0 Flammability 0 Reactivity 0
Dangers
Magnesium sulfate
None
Nonhazardous Component
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.