Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]
H320 - Serious Eye Damage/Eye Irritation (Category 2B)
2.2 Label Elements
| GHS Label Elements | ||
 | WARNING H320 - Causes eye irritation. | |
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Ammonium alum | 5 - 10 | 7784-26-1 | 232-055-3 | N.A. |
| Ethanol | < 10 | 64-17-5 | 200-578-6 | H225, H319 |
| Hematoxylin | < 1 | 517-28-2 | N.A. | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove victim to fresh air. Get medical attention if irritation persists.
Ingestion
If small quantities are swallowed, rinse out mouth with water. Do not induce vomiting. Never give anything by mouth to an unconscious or drowsy person. If large amounts are swallowed or if irritation or discomfort occurs, get medical attention.
Skin
Wash with soap and water. Get medical attention if irritation develops. Remove contaminated clothing and launder before reuse
Eyes
Flush eye with water while lifting the upper and lower lids apart. Get medical attention if irritation persists.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Ammonium alum:
No information found.
Ethanol:
Cough, drowsiness, headache and fatigue.
Hematoxylin:
No information found.
Ingestion
Ammonium alum:
No information found.
Ethanol:
Burning sensation, confusion. dizziness, headacheand unconsciousness.
Hematoxylin:
No information found.
Skin
Ammonium alum:
No information found.
Ethanol:
Dryness.
Hematoxylin:
No information found.
Eyes
Ammonium alum:
No information found.
Ethanol:
Redness, pain and burning.
Hematoxylin:
No information found.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Use any media suitable for the surrounding fire.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Toxic oxides of nitrogen, sulfur.
Hazardous Decomposition Products
Thermal breakdown of this product during fire or very high heat conditions may evolve the following decomposition products: oxides of carbon, nitrogen and sulfur.
Hazardous Polymerization
Not expected to occur.
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment. Eliminate all ignition sources and ventilate the area. Prevent entry into basements or confined areas.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Stop spill at the source if it is safe to do so. Absorb with an inert material. Use non-sparking tools and equipment.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid eye and skin contact. Avoid breathing vapors. Use with adequate ventilation. Wash thoroughly after handling. Removing contaminated clothing and launder before reuse.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep product away from heat, sparks and all other sources of ignition. Keep containers closed when not in use.
Incompatibles
Ammonium alum:
None found.
Ethanol:
Strong oxidants, silver salts, acid chlorides, alkali metals, hydrazine, and many other substances.
Hematoxylin:
None.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Ammonium alum
ACGIH Threshold Limit Value (TLV):
None established
OSHA Permissable Exposure Limit (PEL):
N.A.
Component: Ethanol
ACGIH Threshold Limit Value (TLV):
1000 ppm
OSHA Permissable Exposure Limit (PEL):
None established
Component: Hematoxylin
ACGIH Threshold Limit Value (TLV):
Not determined
OSHA Permissable Exposure Limit (PEL):
Not determined
8.2 Exposure Controls
Engineering Controls
Use with adequate local exhaust ventilation to maintain exposure levels below the the occupational exposure limits.
Respiratory Protection
None needed with adequate protection. If the occupational exposure limit is exceeded use an approved air respirator. Selection of respiratory protection depends on the contaminant type, form and concentration. Select in accordance with OSHA 1910.134 or other applicable regulations and good hygiene practice.
Eye Protection
Wear safety glasses.
Skin Protection
Impervious clothing as needed to avoid skin contact.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Purple liquid | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | N.A. |
| e. Melting/Freezing Point (oC) | -3 | f. Boiling point (oC) | 90 |
| g. Flash Point (oC) | N.A | h. Evaporation Rate | Not determined |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | LEL 3.3%, UEL 19% |
| k. Vapor Pressure | 40 mmHg @ 20 C | l. Vapor Density (Air = 1) | 1.6 |
| m. Relative Density | 1.5 | n. Water Solubility | Soluble in water |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Not reactive under normal conditions of use
10.2 Chemical Stability
Stable unde recommended conditions of use and storage
10.3 Possibility of Hazardous Reactions
Not expected to occur.
10.4 Conditions to Avoid
Heat, sparks flames and all other sources of ignition.
10.5 Incompatible Materials
Ammonium alum:
None found.
Ethanol:
Strong oxidants, silver salts, acid chlorides, alkali metals, hydrazine, and many other substances.
Hematoxylin:
None.
10.6 Hazardous Decomposition Products
Thermal breakdown of this product during fire or very high heat conditions may evolve the following decomposition products: oxides of carbon, nitrogen and sulfur.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
Dermal Rabbit LD50 (mg/kg)
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Ammonium alum | N.A. | N.A. | N.A. |
| Ethanol | No | No | None |
| Hematoxylin | Unknown | N.A. | N.A. |
Potential Health Effects
Inhalation
Ammonium alum
May be harmful if inhaled. Causes respiratory tract irritation.
Ethanol
Can cause irritation to the lungs and upper respiratory tract. May cause headache or fatigue.
Hematoxylin
No information found.
Ingestion
Ammonium alum
May be harmful if swallowed.
Ethanol
May cause irritation or central nervous system effects if swallowed.
Hematoxylin
No information found.
Skin
Ammonium alum
May be harmful if absorbed through skin. Causes skin irritation.
Ethanol
May cause drying or irritation to the skin.
Hematoxylin
No information found.
Eyes
Ammonium alum
Causes eye irritation
Ethanol
May cause irritation to the eyes.
Hematoxylin
No information found.
Carcinogenicity
Ammonium alum
No information found.
Ethanol
Not listed as a known or possible carcinogen by NTP or IARC.
Hematoxylin
Not listed as carcinogen.
Mutagenicity
Ammonium alum
No data available.
Ethanol
No information available.
Hematoxylin
No information found.
Reproductive Toxicity
Ammonium alum
No data available.
Ethanol
Consumption during pregnancy may adversely affect the unborn child.
Hematoxylin
No information found.
Teratogenic Effects
Ammonium alum
No data available.
Ethanol
No information available.
Hematoxylin
No information found.
Routes of Entry
Ammonium alum
No data available.
Ethanol
Inhalation, ingestion, skin contact.
Hematoxylin
Ingestion, inhalation.
Target Organ Statement
Ammonium alum
No data available.
Ethanol
Persons with pre-existing skin disorders or eye problems or impaired liver or kidney function may be more susceptible to the effects of the substance.
Hematoxylin
No information found
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Ammonium alum
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr, zebrafish) 104mg/l | NOEC (48hr, daphnia) >160mg/l | EC50 14mg/l | EC50>1000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Ethanol
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96 hour, fathead minnow) 14g/L | EC50 (48hr, daphnia) 5g/L | EC50 (72hrs) 275mg/L | IC50 >1g/L |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | EC50 155ppm vapor | No data |
COMPONENT: Hematoxylin
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Ammonium alum
No data
Ethanol
Readily biodegradable (95% degradation in 15 days)
Hematoxylin
No data
12.3 Bioaccumulative Potential
Ammonium alum
No data
Ethanol
No data
Hematoxylin
No data
12.4 Mobility in Soil
Ammonium alum
No data
Ethanol
No data
Hematoxylin
No data
12.5 Results of PBT and vPvB Assessment
Ammonium alum
No data
Ethanol
Not PBT or vPvB
Hematoxylin
No data
12.6 Other Adverse Effects
Ammonium alum
None
Ethanol
None
Hematoxylin
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | N.A. | N.A. | N.A. | N.A. |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
N.A.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Ammonium alum | No | No | No | Yes | No |
| Ethanol | Yes | No | No | Yes | Yes |
| Hematoxylin | N.A | N.A | N.A | N.A. | N.A |
Europe
EEC Regulatory
N.A.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
12/13/2013 - Released Version 1.0
NFPA Codes
Health 1 Flammability 1 Reactivity 0
Dangers
Ammonium alum
None
Ethanol
H225 - Highly flammable liquid and vapor.
H319 - Causes serious eye irritation.
Hematoxylin
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.