Version 3.1
Date revised: 8/8/2023

SAFETY DATA SHEETNational Diagnostics

Conforms to regulation (EC) no. EU 453/2010

SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

1.1 Product Identifier

Product Name: Histosol Product Number: HS-100

1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against

Investigational research by professional users

1.3 Details of the Supplier of the Safety Data Sheet

Manufacturer
National Diagnostics
305 Patton Drive
Atlanta, GA 30036
(404) 699-2121
(800) 526-3867
info@nationaldiagnostics.com

1.4 Emergency Telephone Number

ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)

SECTION 2 - HAZARDS IDENTIFICATION

2.1 Classification of the Substance or Mixture

Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]

H226 - Flammable Liquids (Category 3)
H304 - Aspiration Hazard (Category 1)
H315 - Skin Corrosion/Irritation (Category 2)
H336 - May cause drowsiness or dizziness
H411 - Chronic Hazards to the Aquatic Environment (Category 2)

2.2 Label Elements

GHS LABEL ELEMENTS AND CLASSIFICATION
GHS Label Elements
FlammableHuman Health Hazard

DANGER

H226 - Flammable liquid and vapor.
H304 - May be fatal if swallowed and enters airways.
H315 - Causes skin irritation.
H336 - May cause drowsiness or dizziness.
H411 - Toxic to aquatic life with long lasting effects.
P260 - Do not breathe dust/fumes/gas/mist/vapors/spray.
P273 - Avoid release to the environment.
P301+P310 - IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician .
P331 - Do NOT induce vomiting.
P233 - Keep container tightly closed.

Environmental Hazard 
  

2.3 Other Hazards

None found.

SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS

3.2 Mixture

Chemical Names/Description

Light Aromatic Solvent Naphtha


Component List

Component % Comp. CAS # EC # 1278/2008 Classification
Solvent Naphtha, Light Aromatic100 64742-95-6  265-199-0 H226, H304, H315, H336, H411


SECTION 4 - FIRST AID MEASURES

4.1 Description of First Aid Measures

Inhalation

Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion

Do not induce vomiting. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.

Skin

Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eyes

Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.

4.2 Most Important Symptoms and Effects, Both Acute and Delayed

Inhalation

Symptoms may include sore throat, coughing, labored breathing, sneezing and burning sensation, depending on the concentration and duration of exposure. If CNS depression or effects occur, symptoms include headache, excitation, euphoria, dizziness, incoordination, drowsiness, light-headedness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death, depending on the concentration and duration of exposure.

Ingestion

Ingestion symptoms may include salivation, pain, nausea, vomiting, and diarrhea. Exposure may also cause central nervous system symptoms similar to those listed under Inhalation

Skin

Reddening, itching, and inflammation.

Eyes

Irritation, redness, tearing, and blurred vision.

4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed

Unknown/not applicable

SECTION 5 - FIRE FIGHTING MEASURES

5.1 Extinguishing media

Dry powder, foam, carbon dioxide. (Water may be ineffective.)

5.2 Special Hazards Arising from the Substance/Mixture

Hazardous Combustion Products

Thermal decomposition products may include toxic oxides of nitrogen, sulfur, and carbon.

Hazardous Decomposition Products

Combustion may produce oxides of carbon, nitrogen, and sulfur.

Hazardous Polymerization

Will not occur under normal conditions of use (See Sections 10.4 & 10.5).

5.3 Advice for Firefighters

In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.

5.4 Further Information

No data available.

SECTION 6 - ACCIDENTAL RELEASE MEASURES

6.1 Personal Precautions

Wear appropriate protective equipment as specified in Section 8.

6.2 Environmental Precautions

Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.

6.3 Methods and Materials for Containment and Cleaning Up

Isolate hazard area and deny entry. Keep ignition sources out of area and shut off all ignition sources. Absorb spill with inert material (e.g. dry sand or earth) then place in a chemical waste container.

6.4 References to Other Sections

For disposal information see Section 13. For protective clothing and equipment see Section 8.

SECTION 7 - HANDLING AND STORAGE

7.1 Precautions for Safe Handling

Ground lines and equipment used during transfer to reduce the possibility of static spark-initiated fire or explosion. Use non-sparking tools. Do not eat, drink or smoke in areas of use or storage.

7.2 Conditions for Safe Storage (including any incompatibles)

Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage. Isolate from incompatible materials (section 10).

Incompatibles

Oxidizing agents.

7.3 Specific End Uses

Investigational research by professional users

SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS

8.1 Control Parameters

ACGIH Threshold Limit Value (TLV):

50 ppm

OSHA Permissible Exposure Limit (PEL):

None established

8.2 Exposure Controls

Engineering Controls

A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.

Respiratory Protection

For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.

Eye Protection

Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

Skin Protection

Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.


SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES

9.1 Information on Basic Physical & Chemical Properties

a. AppearanceClear, colorles liquidb. OdorModerate aromatic odor
c. Odor ThresholdN.A.d. pHneutral
e. Melting/Freezing Point (oC)-14f. Boiling point (oC)161-171
g. Flash Point (oC)44h. Evaporation Ratevery slow
i. FlammabilityCombustiblej. Upper/Lower Flammability or Explosive LimitsND
k. Vapor Pressure< 10 mm Hg @ 68 Fl. Vapor Density (Air = 1)3.5
m. Relative Density0.87 @ 60 Fn. Water Solubilitynegligible
o. Partition Coefficient n-octanol/waterN.A.p. Autoignition Temperature (oC)463
q. Decomposition Temperature (oC)Not applicable.r. ViscosityNo data available.
s. Explosive Propertiescombustible liquid an vaporst. Oxidizing PropertiesNot an oxidizer

SECTION 10 - STABILITY AND REACTIVITY

10.1 Reactivity

Reacts with strong oxidizers. Combustible vapors- avoid ignition sources.

10.2 Chemical Stability

Stable under recommended conditions of use and storage.

10.3 Possibility of Hazardous Reactions

Will not occur under normal conditions of use (See Sections 10.4 & 10.5).

10.4 Conditions to Avoid

Heat, sources of ignition.

10.5 Incompatible Materials

Oxidizing agents.

10.6 Hazardous Decomposition Products

Combustion may produce oxides of carbon, nitrogen, and sulfur.

SECTION 11 - TOXICOLOGICAL INFORMATION

Product LD50 Values

Oral Rat LD50 (mg/kg)

no data available

Dermal Rabbit LD50 (mg/kg)

no data available

Component Cancer List Status

 NTP Carcinogen 
 KnownAnticipatedIARC Category
Solvent Naphtha, Light AromaticNoNo3

Potential Health Effects

Inhalation

SLIGHTLY TOXIC. Breathing of the mists, vapors or fumes may irritate the nose, throat, and lungs. May cause central nervous system depression or effects. May cause cardiac sensitization, including arrhythmias (irregular heart beats) and death due to cardiac arrest. Chronic exposure to high doses may damage the peripheral nerves, resulting in numbness or tingling in the extremities. See also Reproductive Toxicity and Target Organ Statement for further special toxic effects.

Ingestion

MODERATELY TOXIC. May cause irritation of the mouth, throat, and gastrointestinal tract. Aspiration into lungs may cause chemical pneumonia and lung damage. Aspiration symptoms may be delayed in onset by up to 24 hours. Exposure may also cause central nervous system symptoms similar to those listed under Signs and Symptoms of Overexposure - Inhalation. See also Reproductive Toxicity and Target Organ Statement for further special toxic effects.

Skin

SLIGHTLY IRRITATING. Contact may cause reddening, itching and inflammation. Repeated or prolonged skin contact may cause reddening, itching and inflammation. Defatting agent.

Eyes

SLIGHTLY IRRITATING. Exposure to vapors, fumes or mists may cause irritation. Direct contact may cause irritation, redness, tearing, and blurred vision. Prolonged or repeated exposure may cause irritation and conjunctivitis.

Carcinogenicity

Benzene, a known carcinogen, may be present in trace amounts, less than 50 ppm. Otherwise, there are no known or anticipated carcinogens present in Naphtha.

Mutagenicity

No information available.

Reproductive Toxicity

This product contains components which may cause adverse reproductive effects. Pregnant women may be at an increased risk from exposure. Consumption of alcoholic beverages may enhance toxic effects.

Teratogenic Effects

This product contains components which may cause adverse developmental effects. Pregnant women may be at an increased risk from exposure. Consumption of alcoholic beverages may enhance toxic effects.

Routes of Entry

Inhalation, ingestion, or skin contact.

Target Organ Statement

Acute or chronic overexposure to this material or its components may cause systemic toxicity, including adverse effects to the following: kidney, liver, spleen, adrenals, thymus and central nervous system. Pre-existing medical conditions which may be aggravated by exposure include disorders of the skin, kidney, liver, cardiovascular and respiratory systems.

SECTION 12 - ECOLOGICAL INFOMATION

12.1 Toxicity

 VertebratesInvertebratesAlgaeMicroorganisms
Aquatic Toxicity
(ppm unless otherwise noted)
LL50 (96 hr, fathead minnow) 8.2mg/lEL50 (48hr, daphnia) 4.5mg/lEL50 3.1mg/lEL50 15mg/l

 BirdsArthropodsPlantsMicroorganisms
Terrestrial Environment Toxicity
(ppm unless otherwise noted)
No dataPNEC 0.4-20 mg/lPNEC 0.4-20 mg/lPNEC 0.4-20 mg/l

12.2 Persistence and Degradability

Inherently biodegradable: 74% elimination in 28 days

12.3 Bioaccumulative Potential

No data

12.4 Mobility in Soil

log Koc ~2

12.5 Results of PBT and vPvB Assessment

not PBT / vPvB

12.6 Other Adverse Effects

None


SECTION 13 - DISPOSAL CONSIDERATIONS

13.1 Waste Treatment Methods

Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.


SECTION 14 - TRANSPORT INFORMATION

  ADR/RID IATA IMO DOT
14.1 UN Number 126812681268N.A.
14.2 Shipping NamePetroleum Products N.O.S. (Naphtha Solvent)Petroleum Products, N.O.S.Petroleum Products N.O.S. (Naphtha Solvent)Not regulated
14.3 Hazard Class333N.A.
14.4 Packing GroupIIIIIIIIIN.A.
14.5 Environmental HazardsN.A.N.A.Marine pollutant in excess of 5 kilograms/5 litersN.A.
14.6 Special PrecautionsN.A.N.A.N.A.N.A.

SECTION 15 - REGULATORY INFORMATION

15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture

United States

TSCA Regulatory Statement

All intentional ingredients are listed on the TSCA Inventory.

SARA 311/312 Hazard Categories
ComponentFirePressureReactivityAcuteChronic
Solvent Naphtha, Light AromaticYesNoNoYesYes

Europe

EEC Regulatory

All intentional ingredients are listed on the European EINECS Inventory.

SECTION 16 - OTHER INFORMATION

Revisional Updates

8/8/2023 - Updated Section 14.5
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.1
8/12/2013 - Released Version 1.0

NFPA Codes

Health 1   Flammability 2  Reactivity 0

Dangers

Solvent Naphtha, Light Aromatic

H226 - Flammable liquid and vapor.
H304 - May be fatal if swallowed and enters airways.
H315 - Causes skin irritation.
H336 - May cause drowsiness or dizziness.
H411 - Toxic to aquatic life with long lasting effects.

MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.