Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Not a hazardous substance or mixture according to regulation (EC) No. 1272/2008.
2.2 Label Elements
This product has no labeling elements associated with EC directives or respective national laws.
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Alkaline formamide loading buffer
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Formamide | 95 | 75-12-7 | 200-842-0 | H351, H360 |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
DO NOT INDUCE VOMITING. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Symptoms may include coughing, shortness of breath. Excessive inhalation of vapor may cause symptoms that parallel ingestion, ranging from headache to unconsciousness, depending upon the duration and level of the exposure.
Ingestion
May cause headache, dizziness, nausea, vomiting, abdominal pain, and unconsciousness. May affect the repoductive system.
Skin
Symptoms include redness, itching, and pain. May be absorbed through the skin with symptoms parallel to ingestion.
Eyes
Redness and pain.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Use media appropriate to the primary cause of fire.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
N.A.
Hazardous Decomposition Products
Sodium oxide. Decomposition by reaction with certain metals releases flammable and explosive hydrogen gas.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Contain spills with absorbing material such as sawdust. Sweep and place in covered disposal container. Wash area with water.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area. Protect from physical damage. Isolate from incompatible materials (section 10).
Incompatibles
Acids, alkalines, iodine, pyridine, and sulfur trioxide. Copper, brass, lead, and rubber are attacked by formamide.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
ACGIH Threshold Limit Value (TLV):
10 ppm TWA
OSHA Permissible Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
For conditions of use where exposure to the dust or mist is apparent, a full-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear protective gloves and clean body covering clothing.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear colorless solu | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | 13 - 14 |
| e. Melting/Freezing Point (oC) | 2-3 | f. Boiling point (oC) | 210 |
| g. Flash Point (oC) | 154 | h. Evaporation Rate | N.A. |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.A. |
| k. Vapor Pressure | 1mbar @700 deg C | l. Vapor Density (Air = 1) | > 1.0 |
| m. Relative Density | 1.1300 g/cm3 | n. Water Solubility | 1 g/ 0.9 ml water |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | N.A. |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
10.2 Chemical Stability
Stable under ordinary conditions of use and storage. Very hygroscopic. Can slowly pick up moisture from air and react with carbon dioxide from air to form sodium carbonate.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Moisture, dusting, and incompatibles.
10.5 Incompatible Materials
Acids, alkalines, iodine, pyridine, and sulfur trioxide. Copper, brass, lead, and rubber are attacked by formamide.
10.6 Hazardous Decomposition Products
Sodium oxide. Decomposition by reaction with certain metals releases flammable and explosive hydrogen gas.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
Dermal Rabbit LD50 (mg/kg)
50000
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Formamide | No | No | None |
Potential Health Effects
Inhalation
Causes irritation to the respiratory tract.
Ingestion
Causes irritation to the gastrointestinal tract. Affects the central nervous system. May affect the reproductive system.
Skin
Causes irritation to the skin. May be absorbed through the skin.
Eyes
Causes irritation to the eyes.
Carcinogenicity
Not listed as a known or anticipated carcinogen by NTP or IARC.
Mutagenicity
No information found.
Reproductive Toxicity
May cause congenital malformation of the fetus.
Teratogenic Effects
May cause congenital malformation of the fetus.
Routes of Entry
Ingestion, inhalation, and absorption through the skin.
Target Organ Statement
No information found.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | 6569 @ 96 hrs | >500 @ 48 hrs | >500 @ 96 hrs | >1000 @ 30min |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | no data | no data | no data | no data |
12.2 Persistence and Degradability
Readily biodegradable (99% degradation at 28 days)
12.3 Bioaccumulative Potential
low expected bioaccumulation log BCF 0.5
12.4 Mobility in Soil
log Koc: 0.93
12.5 Results of PBT and vPvB Assessment
No Data
12.6 Other Adverse Effects
No data
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | Not regulated. | Not regulated. | Not regulated. | Not regulated. |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Formamide | No | No | No | Yes | Yes |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
4/16/2013 - Released Version 1.0
NFPA Codes
Health 3 Flammability 1 Reactivity 2
Dangers
Formamide
H351 - Suspected of causing cancer.
H360 - May damage fertility or the unborn child.
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.