Version 3.1
Date revised: 8/8/2023
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Classification according to Regulation (EC) No. 1272/2008 [EU-GHS/CLP]
H301 - Acute Toxicity-Oral (Category 3)
H310 - Acute Toxicity-Dermal (Category 2)
H315 - Skin Corrosion/Irritation (Category 2)
H317 - Skin Sensitizer (Category 1)
H318 - Serious Eye Damage/Eye Irritation (Category 1)
H331 - Acute Toxicity-Inhalation (Category 3)
H373 - Specific Target Organ Toxicity Following Repeated Exposure (Category 2)
H400 - Acute Hazards to the Aquatic Environment (Category 1)
H410 - Chronic Hazards to the Aquatic Environment (Category 1)
2.2 Label Elements
| GHS Label Elements | ||
 |  | DANGER H301 - Toxic if swallowed |
 |  | |
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.1 Substance
Chemical Names/Description
Thioglycol; 2-Thioethanol, 2-Hydroxyetyl mercaptan; Monothioethylene glycol
Chemical Formula
C2H6OS
Component List
| Component | % Comp. | CAS # | EC # |
|---|---|---|---|
| 2-Mercaptoethanol | 100 | 60-24-2 | 200-464-6 |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Call a physician.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Symptoms may include coughing, sore throat, shortness of breath, headaches, nausea, and vomiting. Prolonged exposure can cause CNS stimulation.
Ingestion
Symptoms may include sore throat, abdominal pain, and vomiting.
Skin
Symptoms may include skin irritation.
Eyes
Symptoms may include redness and pain.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Dry powder, foam, carbon dioxide. (Water may be ineffective.)
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Highly toxic gases may be involved in fires of this product.
Hazardous Decomposition Products
Burning may produce sulfur oxides.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Eliminate source of ignition. Ventilate area. Cover with absorbent material (soda ash) to confine spill and sweep or shovel into container. Close container tightly. Avoid breathing vapors.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Use explosion proof ventilation.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage. Isolate from incompatible materials (section 10).
Incompatibles
Oxidizing agents, moisture, Avoid contact with metals.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
ACGIH Threshold Limit Value (TLV):
Not Established
OSHA Permissible Exposure Limit (PEL):
AIHA WEEL 0.2ppm, 8 hr. TWA
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
If the exposure limit is exceeded, wear a supplied air, full-facepiece respirator, airlined hood, or full-facepiece self-contained breathing apparatus. This substance has questionable warning properties.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, colorless liquid | b. Odor | Strong stench |
| c. Odor Threshold | ~1ppm | d. pH | No information found |
| e. Melting/Freezing Point (oC) | -100C (-148F) | f. Boiling point (oC) | 157°C (315F) |
| g. Flash Point (oC) | 74 | h. Evaporation Rate | No information found |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | lel: 2.3%; uel 18% |
| k. Vapor Pressure | 1 @ 20C (68F) | l. Vapor Density (Air = 1) | 2.7 |
| m. Relative Density | 1.114 | n. Water Solubility | Miscible in water |
| o. Partition Coefficient n-octanol/water | log Pow 0.029 | p. Autoignition Temperature (oC) | 295°C |
| q. Decomposition Temperature (oC) | N.A. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Reducing agent- will react with oxidizers.
10.2 Chemical Stability
Stable under ordinary conditions of use and storage. Decomposes under the influence of moisture, water, and acids, forming toxic and combustible gas (hydrogen sulfide).
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Heat, ignition sources, moisture, incompatibles.
10.5 Incompatible Materials
Oxidizing agents, moisture, Avoid contact with metals.
10.6 Hazardous Decomposition Products
Burning may produce sulfur oxides.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
244
Dermal Rabbit LD50 (mg/kg)
150
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| 2-Mercaptoethanol | No | No | None |
Potential Health Effects
Inhalation
Vapors irritate the mucous membranes and respiratory tract.
Ingestion
Toxic. Harmful if swallowed. Sore throat, abdominal pain and vomiting may occur.
Skin
Toxic. Causes skin irritation and may be absorbed in the body in toxic quantities.
Eyes
Vapors irritate the eyes with redness and pain. Splashes may cause severe irritation.
Carcinogenicity
Substance is neither a known nor an anticipated carcinogen. Not listed by NTP, IARC, or OSHA.
Mutagenicity
No information available.
Reproductive Toxicity
No information available.
Teratogenic Effects
No information available.
Routes of Entry
Toxic effects possible by inhalation, ingestion, and skin absorption.
Target Organ Statement
Behavioral: Tremor, convulsion, excitement, muscle contraction/spasticity. Lungs, thorax: Respiratory depression. GI: Changes in structure/function of salivary glands.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr, golden orfe) 37 mg/L | EC50 (daphnia, 48 hr) 0.4 mg/L | LC50 (96h) : 19 mg/L | EC50 (17 h) : 113 mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Biodegradable (90% in 28 days)
12.3 Bioaccumulative Potential
No data
12.4 Mobility in Soil
Koc 1.325
12.5 Results of PBT and vPvB Assessment
Not a PBT or vPvB
12.6 Other Adverse Effects
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | 2966 | 2966 | 2966 | 2966 |
| 14.2 Shipping Name | Thioglycol | Thioglycol | Thioglycol | Thioglycol |
| 14.3 Hazard Class | 6.1 | 6.1 | 6.1 | 6.1 |
| 14.4 Packing Group | II | II | II | II |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| 2-Mercaptoethanol | Yes | No | No | Yes | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
8/8/2023 - Updated Section 14.5
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.1
8/12/2013 - Released Version 1.0
NFPA Codes
Health 3 Flammability 2 Reactivity 0
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.