Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Not a hazardous substance or mixture according to regulation (EC) No. 1272/2008.
2.2 Label Elements
This product has no labeling elements associated with EC directives or respective national laws.
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Aqueous buffer
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Potassium Chloride | 1 | 7447-40-7 | 231-211-8 | N.A. |
| Sodium Chloride | 7.5 | 7647-14-5 | 231-598-3 | N.A. |
| Dipotassium Phosphate | 40.5 | 7758-11-4 | 231-834-5 | N.A. |
| Sodium Phosphate | 1 | 7558-79-4 | 231-448-7 | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Call a physician.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Potassium Chloride:
Inhalations of high concentrations of dust may cause nasal or lung irritation.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Not expected to be a health hazard by inhalation.
Sodium Phosphate:
Not expected to be a health hazard by inhalation.
Ingestion
Potassium Chloride:
Large quantities can produce gastrointestinal irritation and vomiting.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Symptoms may include vomiting, lethargy, diarrhea, blood chemistry effects, cardiac effects and central nervous system effects.
Sodium Phosphate:
No data found.
Skin
Potassium Chloride:
May cause skin irritation.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
No adverse effects expected.
Sodium Phosphate:
No adverse effects expected
Eyes
Potassium Chloride:
Causes eye irritation. May cause chemical conjunctivitis.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Pain and redness.
Sodium Phosphate:
Pain and redness
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
Water spray, dry chemical, alcohol-resistant foam, or carbon dioxide.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
Highly toxic gases may be involved in fires of this product.
Hazardous Decomposition Products
Oxides of the contained metal and halogen, possibly also free, or ionic halogen
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Use absorbent material to collect and contain for salvage or disposal.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area.
Incompatibles
Potassium Chloride:
Bromine trifluoride; potassium permanganate plus sulfuric acid.
Sodium Chloride:
No incompatibility data found.
Dipotassium Phosphate:
No incompatibility data found.
Sodium Phosphate:
Acids, alkaloids, lead acetate, antipyrine, chloral hydrate, resorcinol and pyrogallol.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Potassium Chloride
ACGIH Threshold Limit Value (TLV):
10 mg/m3
OSHA Permissable Exposure Limit (PEL):
15 mg/m3
Component: Sodium Chloride
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
Component: Dipotassium Phosphate
ACGIH Threshold Limit Value (TLV):
10 mg/m3 total dust
OSHA Permissable Exposure Limit (PEL):
15 mg/m3 total dust
Component: Sodium Phosphate
ACGIH Threshold Limit Value (TLV):
None established
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
For conditions of use where exposure to the dust or mist is apparent, a full-face dust/mist respirator may be worn. For emergencies or instances where the exposure levels are not known, use a full-face positive-pressure, air-supplied respirator.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear protective gloves and clean body covering clothing.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Clear, colorless solution | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | 7 |
| e. Melting/Freezing Point (oC) | -5 | f. Boiling point (oC) | 106 |
| g. Flash Point (oC) | N.A. | h. Evaporation Rate | N.A. |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.A. |
| k. Vapor Pressure | N.A. | l. Vapor Density (Air = 1) | N.A. |
| m. Relative Density | N.A. | n. Water Solubility | Miscible |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | Not an oxidizer |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
Non reactive under normal conditions of use.
10.2 Chemical Stability
Stable under recommended conditions of use and storage.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
No information found.
10.5 Incompatible Materials
Potassium Chloride:
Bromine trifluoride; potassium permanganate plus sulfuric acid.
Sodium Chloride:
No incompatibility data found.
Dipotassium Phosphate:
No incompatibility data found.
Sodium Phosphate:
Acids, alkaloids, lead acetate, antipyrine, chloral hydrate, resorcinol and pyrogallol.
10.6 Hazardous Decomposition Products
Oxides of the contained metal and halogen, possibly also free, or ionic halogen
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
260000
Dermal Rabbit LD50 (mg/kg)
No data
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Potassium Chloride | No | No | None |
| Sodium Chloride | No | No | None |
| Dipotassium Phosphate | No | No | None |
| Sodium Phosphate | No | No | None |
Potential Health Effects
Inhalation
Potassium Chloride
May cause respiratory tract irritation. Can produce delayed pulmonary edema.
Sodium Chloride
May cause respiratory tract irritation.
Dipotassium Phosphate
Not expected to be a health hazard by inhalation.
Sodium Phosphate
No data found.
Ingestion
Potassium Chloride
May produce weakness and circulatory problems. May affect heart. In severe cases, ingestion may be fatal.
Sodium Chloride
Ingestion of large amounts may cause gastrointestinal irritation. Ingestion of large amounts may cause nausea and vomiting, rigidity or convulsions. Continued exposure can produce a coma, dehydration and internal organ congestion.
Dipotassium Phosphate
Phosphates are slowly and incompletely absorbed when ingested, and seldom result in systematic effects. Some adverse health effects have occurred. The toxicity of phosphates is because of their ability to sequester calcium. Acute potassium intoxication by mouth is rare because large single doses usually induce vomiting and because in the absence of pre-existing kidney damage, potassium is rapidly excreted. Potassium poisoning can result in heart effects.
Sodium Phosphate
Phosphates are slowly and incompletely absorbed when ingested, and seldom result in systematic effects. Some adverse health effects have occurred. The toxicity of phosphates is because of their ability to sequester calcium.
Skin
Potassium Chloride
Contact may cause irritation or rash, particulary with moist skin.
Sodium Chloride
May cause skin irritation.
Dipotassium Phosphate
No adverse effects expected.
Sodium Phosphate
No data available.
Eyes
Potassium Chloride
Potassium chloride is moderate eye irritant. Redness, tearing, possible abrasion can occur.
Sodium Chloride
May cause eye irritation.
Dipotassium Phosphate
No adverse effects expected but may cause mechanical irritation.
Sodium Phosphate
No data available
Carcinogenicity
Potassium Chloride
Not listed by ACGIH, IARC, NIOSH, NTP, OR OSHA.
Sodium Chloride
Not listed by ACGIH, IARC, NIOSH, NTP or OSHA.
Dipotassium Phosphate
Not listed as a known or anticipated carcinogen by NTP or IARC.
Sodium Phosphate
Not listed as a known or anticipated carcinogen by NTP or IARC.
Mutagenicity
Potassium Chloride
Unscheduled DNA Synthesis: Oral, rat = 1500 ug/kg.; Mutation in Microorganisms = Mouse, Lymphocyte = 2048 mg/L.; DNA Damage = Hamster, Ovary = 260 mmol/L.; Cytogenetic Analysis: Hamster, Lung = 12 gm/L
Sodium Chloride
See actual entry in RTECS for complete information.
Dipotassium Phosphate
No information found.
Sodium Phosphate
No information found.
Reproductive Toxicity
Potassium Chloride
No information available.
Sodium Chloride
No data available.
Dipotassium Phosphate
No information found.
Sodium Phosphate
Teratogenic Effects
Potassium Chloride
No information available.
Sodium Chloride
No information found.
Dipotassium Phosphate
No information found.
Sodium Phosphate
No information found.
Routes of Entry
Potassium Chloride
Ingestion, inhalation, skin and eye contact.
Sodium Chloride
No information found.
Dipotassium Phosphate
No information found.
Sodium Phosphate
No information found.
Target Organ Statement
Potassium Chloride
Sodium Chloride
No information found.
Dipotassium Phosphate
Persons with impaired kidney function may be more susceptible to the effects of the substance.
Sodium Phosphate
No information found.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Potassium Chloride
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr, Fathead minnow) 880mg/L | EC50 (48hr, Daphnia) 440-880 mg/L | EC50 (72hrs) >100mg/L | EC50 (3hr) >1000mg/L |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Sodium Chloride
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hrs, bluegill) 5480 mg/L | LC50 (48 hr, daphnia) 874mg/L | LC50 (120hrs) 2430 mg/L | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | LD50 (house sparrow) 3500mg/kg | No data | IC50 (7 days) 500-1950mg/kg soil | No data |
COMPONENT: Dipotassium Phosphate
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr trout) >100mg/l | EC50 (48hr, daphnia) >100mg/l | EC50 > 100mg/l | EC50 >1000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Sodium Phosphate
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr, trout) >100mg/l | LC50 (zebra mussel) 92mg/l | EC50 > 100mg/l | EC50 > 1000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Potassium Chloride
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Sodium Phosphate
No data
12.3 Bioaccumulative Potential
Potassium Chloride
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Sodium Phosphate
No data
12.4 Mobility in Soil
Potassium Chloride
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Sodium Phosphate
No data
12.5 Results of PBT and vPvB Assessment
Potassium Chloride
No data
Sodium Chloride
Not PBT or vPvB
Dipotassium Phosphate
No data
Sodium Phosphate
Mineral salt
12.6 Other Adverse Effects
Potassium Chloride
None
Sodium Chloride
None
Dipotassium Phosphate
None
Sodium Phosphate
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | Not regulated. | Not regulated. | Not regulated. | Not regulated. |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Potassium Chloride | No | No | No | Yes | No |
| Sodium Chloride | No | No | No | Yes | No |
| Dipotassium Phosphate | No | No | No | Yes | Yes |
| Sodium Phosphate | No | No | No | No | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
10/24/2013 - Released Version 1.0
NFPA Codes
Health 1 Flammability 0 Reactivity 0
Dangers
Potassium Chloride
None
Sodium Chloride
None
Dipotassium Phosphate
None
Sodium Phosphate
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.