Version 3.0
Date revised: 4/26/2019
SAFETY DATA SHEET
Conforms to regulation (EC) no. EU 453/2010
SECTION 1 - IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING
1.1 Product Identifier
1.2 Relevant Identified Uses of the Substance/Mixture and Uses Advised Against
Investigational research by professional users
1.3 Details of the Supplier of the Safety Data Sheet
| Manufacturer National Diagnostics 305 Patton Drive Atlanta, GA 30036 (404) 699-2121 (800) 526-3867 info@nationaldiagnostics.com |
1.4 Emergency Telephone Number
ChemTel Inc.
Contract number MIS8894340
1-800 255-3924 (United States, Canada, Puerto Rico & US Virgin Islands)
01-800-099-0731 (Mexico)
400-120-0751 (China)
000-800-100-4086 (India)
1-300-954-583 (Australia)
0-800-591-6042 (Brazil)
+1-813-255-3924 (All other regions)
SECTION 2 - HAZARDS IDENTIFICATION
2.1 Classification of the Substance or Mixture
Not a hazardous substance or mixture according to regulation (EC) No. 1272/2008.
2.2 Label Elements
This product has no labeling elements associated with EC directives or respective national laws.
2.3 Other Hazards
None found.
SECTION 3 - COMPOSITION/INFORMATION ON INGREDIENTS
3.2 Mixture
Chemical Names/Description
Buffered solution with surfactants and 0.1% proprietary preservative.
Component List
| Component | % Comp. | CAS # | EC # | 1278/2008 Classification |
|---|---|---|---|---|
| Proprietary Preservative | 0.1% | H300, H400, H410 | ||
| Sodium Chloride | 5 - 10% | 7647-14-5 | 231-598-3 | N.A. |
| Dipotassium Phosphate | < 5% | 7758-11-4 | 231-834-5 | N.A. |
| Polysorbate 20 | < 5% | 9005-64-5 | 500-018-3 | N.A. |
SECTION 4 - FIRST AID MEASURES
4.1 Description of First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.
Ingestion
Induce vomiting immediately as directed by medical personnel. Never give anything by mouth to an unconscious person. Call a physician.
Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.
4.2 Most Important Symptoms and Effects, Both Acute and Delayed
Inhalation
Proprietary Preservative:
Sore throat, coughing, dizziness, shortness of breath and fainting (also symptoms parallel to ingestion)
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Not expected to be a health hazard by inhalation.
Polysorbate 20:
Not expected to be a health hazard by inhalation.
Ingestion
Proprietary Preservative:
Breathlessness, pulmonary edema and rapid heartbeat within 5 minutes. Nauseau, vomiting, headache, restlessness, and diarrhea may occur within 15 minutes. Other symptoms may include low blood pressure, abnormal breathing, reduced body temperature, reduced body pH, convulsions, collapse and death.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Symptoms may include vomiting, lethargy, diarrhea, blood chemistry effects, cardiac effects and central nervous system effects.
Polysorbate 20:
Abdominal spasms, diarrhea.
Skin
Proprietary Preservative:
Causes irritation, redness, and pain (also symptoms parallel to ingestion)
Sodium Chloride:
No information found.
Dipotassium Phosphate:
No adverse effects expected.
Polysorbate 20:
Redness, swelling.
Eyes
Proprietary Preservative:
Irritation, redness, pain and blurred vision.
Sodium Chloride:
No information found.
Dipotassium Phosphate:
Pain and redness.
Polysorbate 20:
Pain, redness.
4.3 Indication of Any Immediate Medical Attention and Special Treatment Needed
Unknown/not applicable
SECTION 5 - FIRE FIGHTING MEASURES
5.1 Extinguishing media
N.A.
5.2 Special Hazards Arising from the Substance/Mixture
Hazardous Combustion Products
N.A.
Hazardous Decomposition Products
May form lead/copper azide in laboratory plumbing.
Hazardous Polymerization
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
5.3 Advice for Firefighters
N.A.
5.4 Further Information
No data available.
SECTION 6 - ACCIDENTAL RELEASE MEASURES
6.1 Personal Precautions
Wear appropriate protective equipment as specified in Section 8.
6.2 Environmental Precautions
Prevent discharge into the environment. Dike spills and stop leakage where practical. Do not allow material to enter drains.
6.3 Methods and Materials for Containment and Cleaning Up
Contain and clean up spill immediately, prevent from entering floor drains. Contain liquids using absorbents. Shovel all spill materials into disposal drum. Scrub spill area with detergent, flush with copious amounts of water.
6.4 References to Other Sections
For disposal information see Section 13. For protective clothing and equipment see Section 8.
SECTION 7 - HANDLING AND STORAGE
7.1 Precautions for Safe Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling.
7.2 Conditions for Safe Storage (including any incompatibles)
Keep in a tightly closed container, stored in a cooled, dry, ventilated area.
Incompatibles
Proprietary Preservative:
Benzoyl chloride plus potassium hydroxide, bromine, carbon disulfide, chromyl chloride, copper, dibromalononitrile, dimethyl sulfate, lead, barium carbonate, sulfuric acid, nitric acid.
Sodium Chloride:
No incompatibility data found.
Dipotassium Phosphate:
No incompatibility data found.
Polysorbate 20:
Strong oxidizers, acids.
7.3 Specific End Uses
Investigational research by professional users
SECTION 8 - EXPOSURE CONTROLS/PERSONAL PRECAUTIONS
8.1 Control Parameters
Component: Proprietary Preservative
ACGIH Threshold Limit Value (TLV):
None established
OSHA Permissable Exposure Limit (PEL):
None established
Component: Sodium Chloride
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
Component: Dipotassium Phosphate
ACGIH Threshold Limit Value (TLV):
10 mg/m3 total dust
OSHA Permissable Exposure Limit (PEL):
15 mg/m3 total dust
Component: Polysorbate 20
ACGIH Threshold Limit Value (TLV):
none established
OSHA Permissable Exposure Limit (PEL):
None established
8.2 Exposure Controls
Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborne Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.
Respiratory Protection
Not expected to require personal respirator usage.
Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.
Skin Protection
Wear impervious protective clothing, including boots, gloves, lab coat, apron or coveralls, as appropriate, to prevent skin contact.
SECTION 9 - PHYSICAL AND CHEMICAL PROPERTIES
9.1 Information on Basic Physical & Chemical Properties
| a. Appearance | Colorless liquid | b. Odor | None |
| c. Odor Threshold | N.A. | d. pH | 7.4 |
| e. Melting/Freezing Point (oC) | 0 | f. Boiling point (oC) | 100 |
| g. Flash Point (oC) | N.A. | h. Evaporation Rate | as water |
| i. Flammability | N.A. | j. Upper/Lower Flammability or Explosive Limits | N.A. |
| k. Vapor Pressure | as water | l. Vapor Density (Air = 1) | as water |
| m. Relative Density | as water | n. Water Solubility | soluble |
| o. Partition Coefficient n-octanol/water | Mixture | p. Autoignition Temperature (oC) | N.A. |
| q. Decomposition Temperature (oC) | Not applicable. | r. Viscosity | No data available. |
| s. Explosive Properties | N.A. | t. Oxidizing Properties | N.A. |
SECTION 10 - STABILITY AND REACTIVITY
10.1 Reactivity
10.2 Chemical Stability
Stable under normal conditions of use and storage.
10.3 Possibility of Hazardous Reactions
Will not occur under normal conditions of use (See Sections 10.4 & 10.5).
10.4 Conditions to Avoid
Don't store near acids.
10.5 Incompatible Materials
Proprietary Preservative:
Benzoyl chloride plus potassium hydroxide, bromine, carbon disulfide, chromyl chloride, copper, dibromalononitrile, dimethyl sulfate, lead, barium carbonate, sulfuric acid, nitric acid.
Sodium Chloride:
No incompatibility data found.
Dipotassium Phosphate:
No incompatibility data found.
Polysorbate 20:
Strong oxidizers, acids.
10.6 Hazardous Decomposition Products
May form lead/copper azide in laboratory plumbing.
SECTION 11 - TOXICOLOGICAL INFORMATION
Product LD50 Values
Oral Rat LD50 (mg/kg)
27000
Dermal Rabbit LD50 (mg/kg)
20000
Component Cancer List Status
| NTP Carcinogen | |||
| Known | Anticipated | IARC Category | |
|---|---|---|---|
| Proprietary Preservative | No | No | None |
| Sodium Chloride | No | No | None |
| Dipotassium Phosphate | No | No | None |
| Polysorbate 20 | No | No | none |
Potential Health Effects
Inhalation
Proprietary Preservative
Contains 0.1% of a preservative that in concentrated form is highly toxic, causing irritation to the respiratory tract and mucous membranes, sore throat, coughing, dizziness, shortness of breath and fainting.
Sodium Chloride
May cause respiratory tract irritation.
Dipotassium Phosphate
Not expected to be a health hazard by inhalation.
Polysorbate 20
Not expected to be a health hazard by inhalation.
Ingestion
Proprietary Preservative
Contains 0.1% of a preservative which if ingested in quantity may cause breathlessness, pulmonary edema and rapid heartbeat within 5 minutes. Nausea, vomiting, headache, restlessness, and diarrhea may occur within 15 minutes. Other symptoms may include low blood pressure, abnormal breathing, reduced body temperature, reduced body pH, convulsions, collapse and death.
Sodium Chloride
Ingestion of large amounts may cause gastrointestinal irritation. Ingestion of large amounts may cause nausea and vomiting, rigidity or convulsions. Continued exposure can produce a coma, dehydration and internal organ congestion.
Dipotassium Phosphate
Phosphates are slowly and incompletely absorbed when ingested, and seldom result in systematic effects. Some adverse health effects have occurred. The toxicity of phosphates is because of their ability to sequester calcium. Acute potassium intoxication by mouth is rare because large single doses usually induce vomiting and because in the absence of pre-existing kidney damage, potassium is rapidly excreted. Potassium poisoning can result in heart effects.
Polysorbate 20
Large doses may produce abdominal spasms, diarrhea.
Skin
Proprietary Preservative
Contains 0.1% of a preservative which in concentration causes irritation, redness, and pain, may be absorbed through the skin with symptoms parallel to ingestion.
Sodium Chloride
May cause skin irritation.
Dipotassium Phosphate
No adverse effects expected.
Polysorbate 20
May cause irritation or sensitization in sensitive individuals.
Eyes
Proprietary Preservative
Irritation, redness, pain and blurred vision.
Sodium Chloride
May cause eye irritation.
Dipotassium Phosphate
No adverse effects expected but may cause mechanical irritation.
Polysorbate 20
May cause irritation.
Carcinogenicity
Proprietary Preservative
No information found.
Sodium Chloride
Not listed by ACGIH, IARC, NIOSH, NTP or OSHA.
Dipotassium Phosphate
Not listed as a known or anticipated carcinogen by NTP or IARC.
Polysorbate 20
Not listed as a known or anticipated carcinogen by NTP or IARC.
Mutagenicity
Proprietary Preservative
No information found.
Sodium Chloride
See actual entry in RTECS for complete information.
Dipotassium Phosphate
No information found.
Polysorbate 20
No information found.
Reproductive Toxicity
Proprietary Preservative
No information found.
Sodium Chloride
No data available.
Dipotassium Phosphate
No information found.
Polysorbate 20
No information found.
Teratogenic Effects
Proprietary Preservative
No information found.
Sodium Chloride
No information found.
Dipotassium Phosphate
No information found.
Polysorbate 20
No information found.
Routes of Entry
Proprietary Preservative
Inhalation, ingestion, skin contact.
Sodium Chloride
No information found.
Dipotassium Phosphate
No information found.
Polysorbate 20
No information found.
Target Organ Statement
Proprietary Preservative
Sodium azide may affect the nervous system, kidneys, and cardiovascular system.
Sodium Chloride
No information found.
Dipotassium Phosphate
Persons with impaired kidney function may be more susceptible to the effects of the substance.
Polysorbate 20
No information found.
SECTION 12 - ECOLOGICAL INFOMATION
12.1 Toxicity
COMPONENT: Proprietary Preservative
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Sodium Chloride
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hrs, bluegill) 5480 mg/L | LC50 (48 hr, daphnia) 874mg/L | LC50 (120hrs) 2430 mg/L | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | LD50 (house sparrow) 3500mg/kg | No data | IC50 (7 days) 500-1950mg/kg soil | No data |
COMPONENT: Dipotassium Phosphate
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | LC50 (96hr trout) >100mg/l | EC50 (48hr, daphnia) >100mg/l | EC50 > 100mg/l | EC50 >1000mg/l |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
COMPONENT: Polysorbate 20
| Vertebrates | Invertebrates | Algae | Microorganisms | |
|---|---|---|---|---|
Aquatic Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
| Birds | Arthropods | Plants | Microorganisms | |
|---|---|---|---|---|
Terrestrial Environment Toxicity (ppm unless otherwise noted) | No data | No data | No data | No data |
12.2 Persistence and Degradability
Proprietary Preservative
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Polysorbate 20
No data
12.3 Bioaccumulative Potential
Proprietary Preservative
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Polysorbate 20
No data
12.4 Mobility in Soil
Proprietary Preservative
No data
Sodium Chloride
No data
Dipotassium Phosphate
No data
Polysorbate 20
No data
12.5 Results of PBT and vPvB Assessment
Proprietary Preservative
No data
Sodium Chloride
Not PBT or vPvB
Dipotassium Phosphate
No data
Polysorbate 20
No data
12.6 Other Adverse Effects
Proprietary Preservative
None
Sodium Chloride
None
Dipotassium Phosphate
None
Polysorbate 20
None
SECTION 13 - DISPOSAL CONSIDERATIONS
13.1 Waste Treatment Methods
Offer surplus or non-recyclable product to licensed disposal company. Disposal is subject to user compliance with applicable law and product characteristics at time of disposal. Dispose of packaging as product.
SECTION 14 - TRANSPORT INFORMATION
| ADR/RID | IATA | IMO | DOT | |
|---|---|---|---|---|
| 14.1 UN Number | N.A. | N.A. | N.A. | N.A. |
| 14.2 Shipping Name | Not regulated | Not regulated | Not regulated | Not regulated |
| 14.3 Hazard Class | N.A. | N.A. | N.A. | N.A. |
| 14.4 Packing Group | N.A. | N.A. | N.A. | N.A. |
| 14.5 Environmental Hazards | N.A. | N.A. | Not regulated | N.A. |
| 14.6 Special Precautions | N.A. | N.A. | N.A. | N.A. |
SECTION 15 - REGULATORY INFORMATION
15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance/Mixture
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.
SARA 311/312 Hazard Categories
| Component | Fire | Pressure | Reactivity | Acute | Chronic |
|---|---|---|---|---|---|
| Proprietary Preservative | Yes | No | Yes | Yes | Yes |
| Sodium Chloride | No | No | No | Yes | No |
| Dipotassium Phosphate | No | No | No | Yes | Yes |
| Polysorbate 20 | No | No | No | Yes | No |
Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.
SECTION 16 - OTHER INFORMATION
Revisional Updates
4/26/2019 - Updated Section 1.4
5/29/2015 - Updated Sections 2.1 and 3.2
4/16/2013 - Released Version 1.0
NFPA Codes
Health N.A. Flammability N.A. Reactivity N.A.
Dangers
Proprietary Preservative
H300 - Fatal if swallowed.
H400 - Very toxic to aquatic life.
H410 - Very toxic to aquatic life with long lasting effects.
Sodium Chloride
None
Dipotassium Phosphate
None
Polysorbate 20
None
MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.