Most research applications of radioisotopes require an eventual quantitation of the isotope, which is done by measuring the intensity of radiation

A beta particle, passing through a scintillation cocktail, leaves a trail of energized solvent molecules.

Living creatures contain both hydrophobic and hydrophilic compounds, any of which may be labeled during the course of a radioactive experiment.

An aspect of LSC which must be considered in experimental design, is waste disposal.