Date revised: 11/5/2009
MATERIAL SAFETY DATA SHEET
National Diagnostics
Conforms to 93/112/EC and ISO 11014-1

1. Chemical Product and Company Identification
Product Name:
Bioscint
Product Number:
LS-309

Chemical Names/
Description:
 
Mixture of organic solvents, detergents, and phosphors

Manufacturer
 
Telephone Numbers
National Diagnostics
305 Patton Drive
Atlanta, GA 30338
 
(800) 526-3867
(404) 699-2121
 
 
Emergency Number
   
Chemtrec
(800) 424-9300


2. Composition/Information on Ingredients
Component % Comp. CAS # EINECS # TLV (Units)
Phenyl Xylyl Ethane (PXE)60 - 70 6196-95-8     none established 
Linear alkyl phenyl ethoxylates20 - 30 9016-45-9     none established 
Butoxy Ethanol1 - 3 111-76-2  203-805-0  25 ppm (skin) 
Alcohol ethoxylate phosphate ester1 - 3 51811-79-1     none established 



3. Hazards Identification
Appearance and Odor
Clear, colorless liquid

EMERGENCY OVERVIEW - IMMEDIATE HAZARD
Phenyl Xylyl Ethane (PXE)
MAY BE IRRITATING TO THE SKIN, EYES, AND RESPIRATORY TRACT.
Linear alkyl phenyl ethoxylates
CAUSES EYE IRRITATION. MAY CAUSE RESPIRATORY TRACT IRRITATION.
Butoxy Ethanol
CAUTION! SEVERELY IRRITATING TO THE EYES. IRRITATING TO THE SKIN, NOSE THROAT AND RESPIRATORY TRACT. TOXIC IF INHALED, INGESTED OR ABSORBED THROUGH SKIN.
Alcohol ethoxylate phosphate ester
CAUSES EYE IRRITATION. MAY CAUSE RESPIRATORY TRACT IRRITATION.
EMERGENCY OVERVIEW - CHRONIC HAZARD WARNING:
Phenyl Xylyl Ethane (PXE)
NO CHRONIC HEALTH HAZARDS KNOWN
Linear alkyl phenyl ethoxylates
NO ADVERSE EFFECTS HAVE BEEN DOCUMENTED IN HUMANS AS A RESULT OF CHRONIC EXPOSURE.
Butoxy Ethanol
NO INFORMATION FOUND.
Alcohol ethoxylate phosphate ester
NO ADVERSE EFFECTS HAVE BEEN DOCUMENTED IN HUMANS AS A RESULT OF CHRONIC EXPOSURE.
Potential Health Effects
Inhalation
Phenyl Xylyl Ethane (PXE):
Breathing of the mists, vapors or fumes may irritate the nose, throat and lungs.

Linear alkyl phenyl ethoxylates:
Vapors or mist, expecially as generated from heating the material or as from exposure in poorly ventilated areas or confined spaces, may be irritating and cause discomfort in nose and throat. Prolonged exposure may cause difficulty breathing.

Butoxy Ethanol:
Vapors may cause irritation to the nose, throat, and respiratory tract and are toxic if inhaled.

Alcohol ethoxylate phosphate ester:
Vapors or mist, expecially as generated from heating the material or as from exposure in poorly ventilated areas or confined spaces, may be irritating and cause discomfort in nose and throat. Prolonged exposure may cause difficulty breathing.

Ingestion
Phenyl Xylyl Ethane (PXE):
May cause irritation of the mouth, throat, and gastrointestinal tract. Exposure may also cause central nervous system symptoms.

Linear alkyl phenyl ethoxylates:
May be harmful by ingestion.

Butoxy Ethanol:
Moderately toxic if ingested.

Alcohol ethoxylate phosphate ester:
May be harmful by ingestion.

Skin
Phenyl Xylyl Ethane (PXE):
May cause skin irritation.

Linear alkyl phenyl ethoxylates:
Brief contact may cause slight irritation. Prolonged contact, as with clothing wetted with material, may cause more severe irritation and discomfort.

Butoxy Ethanol:
Product is mildly irritating to the skin and toxic if absorbed through the skin.

Alcohol ethoxylate phosphate ester:
Brief contact may cause slight irritation. Prolonged contact, as with clothing wetted with material, may cause more severe irritation and discomfort.

Eyes
Phenyl Xylyl Ethane (PXE):
Exposure to vapors, fumes or mists may cause irritation. Direct contact may cause irritation.

Linear alkyl phenyl ethoxylates:
Causes irritation and possible injury to the cornea.

Butoxy Ethanol:
Causes severe eye irritation.

Alcohol ethoxylate phosphate ester:
Causes irritation and possible injury to the cornea.

Signs and Symptoms of Overexposure
Inhalation
Phenyl Xylyl Ethane (PXE):
Sore throat, coughing, labored breathing, sneezing and burning sensation, depending on the concentration and duration of exposure. May cause central nervous system depression or effects. Symptoms may include headache, excitation, euphoria, dizziness, incoordination, drowsiness, light-headedness, blurred vision, fatigue, tremors, convulsions, loss of consciousness, coma, respiratory arrest and death, depending on the concentration and duration of exposure.

Linear alkyl phenyl ethoxylates:
Discomfort in nose and throat, nasal discharge, coughing, difficulty breathing.

Butoxy Ethanol:
Burning in nose and throat, coughing. Headache, dizziness, drowsiness, fatigue, nausea.

Alcohol ethoxylate phosphate ester:
Discomfort in nose and throat, nasal discharge, coughing, difficulty breathing.

Ingestion
Phenyl Xylyl Ethane (PXE):
Salivation, pain, nausea, vomiting and diarrhea. Exposure may also cause central nervous system symptoms similar to those listed under Inhalation.

Linear alkyl phenyl ethoxylates:
Abdominal discomfort, nausea, and diarrhea.

Butoxy Ethanol:
Headache, dizziness, drowsiness, fatigue, nausea, vomiting.

Alcohol ethoxylate phosphate ester:
Abdominal discomfort, nausea, and diarrhea.

Skin
Phenyl Xylyl Ethane (PXE):
Drying, reddening, itching, and cracking. Repeated or prolonged contact with large amounts of this material may result in absorption through the skin to produce toxic effects.

Linear alkyl phenyl ethoxylates:
Local redness and swelling.

Butoxy Ethanol:
Redness, pain and itching.

Alcohol ethoxylate phosphate ester:
Local redness and swelling.

Eyes
Phenyl Xylyl Ethane (PXE):
Redness, tearing, and blurred vision.

Linear alkyl phenyl ethoxylates:
Excess blinking and tear production. Marked redness and swelling of the eye with injury to the cornea.

Butoxy Ethanol:
Redness, tearing, and pain.

Alcohol ethoxylate phosphate ester:
Excess blinking and tear production. Marked redness and swelling of the eye with injury to the cornea.

Carcinogenicity
Phenyl Xylyl Ethane (PXE):
Not listed by NTP or IARC as a known or possible carcinogen.

Linear alkyl phenyl ethoxylates:
Not listed by NTP or IARC as a known or possible carcinogen.

Butoxy Ethanol:
Not listed as a known or anticipated carcinogen by NTP or IARC.

Alcohol ethoxylate phosphate ester:
Not listed by NTP or IARC as a known or possible carcinogen.

Mutagenicity
Phenyl Xylyl Ethane (PXE):
No information available.

Linear alkyl phenyl ethoxylates:
No information available.

Butoxy Ethanol:
No information found.

Alcohol ethoxylate phosphate ester:
No information available.

Reproductive Toxicitiy
Phenyl Xylyl Ethane (PXE):
No information available.

Linear alkyl phenyl ethoxylates:
No information available.

Butoxy Ethanol:
Inhalation exposure of pregnant rabbits caused some lethality to the dam and fetus at 200 ppm, but there were no effects at 100 ppm and below. Inhalation exposure to pregnant rats caused irritancy to the dams and related fetotoxicity at 200 and 100 ppm, but there were no effects at 50 ppm and below.

Alcohol ethoxylate phosphate ester:
No information available.

Teratogenic Effects
Phenyl Xylyl Ethane (PXE):
No information available.

Linear alkyl phenyl ethoxylates:
No information available.

Butoxy Ethanol:
Has not been shown to cause birth defects.

Alcohol ethoxylate phosphate ester:
No information available.

Routes of Entry
Phenyl Xylyl Ethane (PXE):
Ingestion, inhalation, skin contact.

Linear alkyl phenyl ethoxylates:
Ingestion, inhalation.

Butoxy Ethanol:
Inhalation, ingestion, skin contact.

Alcohol ethoxylate phosphate ester:
Ingestion, inhalation.

Target Organ Statement
Phenyl Xylyl Ethane (PXE):
No information available.

Linear alkyl phenyl ethoxylates:
No information available.

Butoxy Ethanol:
Preexisting skin, eye, and lung disorders may be aggravated by exposure.

Alcohol ethoxylate phosphate ester:
No information available.


4. First Aid Measures
Inhalation
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Call a physician.

Ingestion
DO NOT INDUCE VOMITING. If swallowed and the person is conscious, immediately give large amounts of water. Get medical attention.

Skin
Immediately flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Get medical attention. Wash clothing before reuse. Thoroughly clean shoes before reuse.

Eyes
Immediately flush eyes with plenty of water for at least fifteen minutes, lifting lower and upper eyelids occasionally. Get medical attention immediately.


5. Fire Fighting Measures
Flash Point > 93 C  Flammable Limits N.D. 
Flash Point Method PMCC*  Autoignition temperature N.D. 
* Flash point value determined by Pensky-Martin Closed Cup method (PMCC). Upon request, alternate Tagliabue Closed Cup data (TCC) has been provided in some instances to local regulatory agencies.

Extinguishing media
Water spray, dry chemical, alcohol-resistant foam, or carbon dioxide.

Protective Equipment
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained breathing apparatus with full facepiece operated in the pressure demand or other positive pressure mode.

Hazardous Combustion Products
Fires involving this product may release carbon monoxide, carbon dioxide, reactive hydrocarbons and irritating vapors.

Unusual Fire and Explosion Hazards
Vapors may form explosive mixtures with air. Vapors can travel to a source of ignition and flash back.

NFPA Codes:   Health 1    Flammability 1    Reactivity 0

6. Accidential Release Measures
Steps to be taken in case material is released or spilled
Eliminate source of ignition. Ventilate area. Cover with absorbent material (soda ash) to confine spill and sweep or shovel into container. Close container tightly. Avoid breathing vapors.

Waste Disposal Method
Disposal must be made in accordance with applicable federal, state, and local regulations.

Personal Precautions
Wear appropriate protective equipment as specified in section 8.


7. Handling and Storage
Handling
Avoid contact and inhalation. Do not get in eyes, on skin, on clothing. Wash thoroughly after handling. Transfer methods should avoid static sparks. Do not eat, drink, or smoke in areas of use or storage.

Storage
Keep in a tightly closed container, stored in a cooled, dry, ventilated area away from sources of heat or ignition. Protect from physical damage.

Storage Temperature
Room Temperature

Disposal
Observe all national, state, and local regulations regarding disposal.


8. Exposure Controls/Personal Protection
Airborne Exposure Limits
Component: Phenyl Xylyl Ethane (PXE)
ACGIH Threshold Limit Value (TLV):  none established 
OSHA Permissable Exposure Limit (PEL):    

Component: Linear alkyl phenyl ethoxylates
ACGIH Threshold Limit Value (TLV):  none established 
OSHA Permissable Exposure Limit (PEL):    

Component: Butoxy Ethanol
ACGIH Threshold Limit Value (TLV):  25 ppm (skin) 
OSHA Permissable Exposure Limit (PEL):  25 ppm 

Component: Alcohol ethoxylate phosphate ester
ACGIH Threshold Limit Value (TLV):  none established 
OSHA Permissable Exposure Limit (PEL):    


Engineering Controls
A system of local and/or general exhaust is recommended to keep employee exposures below the Airborn Exposure Limits. Local exhaust ventilation is generally preferred because it can control the emissions of the contaminant at its source.

Respiratory Protection
For conditions of use where exposure to the substance is apparent, consult an industrial hygienist. For emergencies, or instances where the exposure levels are not known, use a full-facepiece positive-pressure, air-supplied respirator.

Eye Protection
Use chemical safety goggles and/or a full face shield where splashing is possible. Maintain eye wash fountain and quick-drench facilities in work area.

Skin Protection
Wear protective gloves and clean body covering clothing.

Other Control Measures
N.A.


9. Physical Properties
Boiling point
575 - 605 F 
Evaporation Rate
Not measureable 
Melting point
N.A. 
Solubity in water
Slightly soluble.  
Vapor pressure (mmHg)
< 0.1 
pH
N.A. 
Vapor density (Air = 1)
Not determinable 
Specific gravity (H2O = 1)
0.91 
% volatile by volume
100% 
   


10. Stability and Reactivity
Stability
Stable under ordinary conditions of use and storage.

Conditions to Avoid
Heat, sources of ignition.

Hazardous Decomposition Products
Combustion may produce toxic oxides of carbon and reactive hydrocarbons.

Hazardous Polymerization
Will not occur

Incompatibles
Phenyl Xylyl Ethane (PXE):
Oxidizing agents.

Linear alkyl phenyl ethoxylates:
Oxidizing agents.

Butoxy Ethanol:
Strong oxidizing agents. Strong bases and salts of strong bases at elevated temperatures. Aluminum surfaces.

Alcohol ethoxylate phosphate ester:
Oxidizing agents.



11. Toxicological Information
Product LD50 Values
BioscintOral Rat LD50 (mg/kg):> 1500 mg/kg
BioscintDermal Rabbit LD50 (mg/kg):No data


Component Cancer List Status
 NTP Carcinogen 
 KnownAnticipatedIARC Category
Phenyl Xylyl Ethane (PXE)NoNoNone
Linear alkyl phenyl ethoxylatesNoNoNone
Butoxy EthanolNoNoNone
Alcohol ethoxylate phosphate esterNoNoNone


12. Ecological Information
Phenyl Xylyl Ethane (PXE)
This product has been evaluated for RCRA characteristics and does not meet the criteria of a hazardous waste if discarded in its purchased form. Under RCRA is is the responsibility of the user to determine, at the time of disposal, whether the product meets the criteria for hazardous waste.

Linear alkyl phenyl ethoxylates
This product has been evaluated for RCRA characteristics and does not meet the criteria of a hazardous waste if discarded in its purchased form. Under RCRA is is the responsibility of the user to determine, at the time of disposal, whether the product meets the criteria for hazardous waste.

Butoxy Ethanol
No information available.

Alcohol ethoxylate phosphate ester
No information available.


13. Disposal Considerations
Observe all national, state, and local regulations regarding disposal.


14. Transport Information
D.O.T.
Proper Shipping Name: Not regulated.
Hazard Class: N.A.
UN Number: N.A.
Packing Group: N.A.

I.A.T.A.
Proper Shipping Name: Not regulated.
Hazard Class: N.A.
UN Number: N.A.
Packing Group: N.A.

I.M.O.
Proper Shipping Name: Not regulated.
Hazard Class: N.A.
UN Number: N.A.
Packing Group: N.A.


15. Regulatory Information
United States
TSCA Regulatory Statement
All intentional ingredients are listed on the TSCA Inventory.

SARA 311/312 Hazard Categories
ComponentFirePressureReactivityAcuteChronic
Phenyl Xylyl Ethane (PXE)NoNoNoYesNo
Linear alkyl phenyl ethoxylatesNoNoNoYesNo
Butoxy EthanolYesNoNoYesNo
Alcohol ethoxylate phosphate esterNoNoNoYesNo

Europe
EEC Regulatory
All intentional ingredients are listed on the European EINECS Inventory.



16. Other Information
NFPA Codes:   Health 1    Flammability 1    Reactivity 0

MANUFACTURER DISCLAIMER: The information given herein is offered in good faith as accurate, but without guarantee. Conditions of the use and suitability of the product for particular uses are beyond our control. All risks of use of the product are therefore assumed by the user. Nothing is intended as a recommendation for uses which infringe valid patents or as extending license under valid patents. Appropriate warnings and safe handling procedures should be provided to handlers and users.